Epithelial Cells of Deep Infiltrating Endometriosis Harbor Mutations in Cancer Driver Genes
نویسندگان
چکیده
منابع مشابه
Laparoscopic rectal resection of deep infiltrating endometriosis.
PURPOSE Deep infiltrating endometriosis with colorectal involvement is a complex disorder, often requiring segmental bowel resection. Complete removal of all visible lesions is considered the adequate treatment of infiltrating endometriosis in order to reduce recurrence. In this article, we describe our experience with laparoscopic management of deep infiltrating endometriosis with involvement ...
متن کاملNDRG2 Regulates the Expression of Genes Involved in Epithelial Mesenchymal Transition of Prostate Cancer Cells
Background: Metastasis is the main cause of prostate cancer (PCa) death. The inhibitory effect of N-myc downstream-regulated gene 2 (NDRG2) on the invasiveness properties of PCa cells has been demonstrated previously. However, its underlying mechanisms have not yet been investigated. The present study aimed to investigate the effects of NDRG2 overexpression on the expression of genes involved i...
متن کاملLeptin, its receptor and aromatase expression in deep infiltrating endometriosis
BACKGROUND The aim of this study was to evaluate the leptin levels in the serum and peritoneal fluid (PF) and the protein expression in three different peritoneal ectopic implants in patients who underwent surgery for deep infiltrating endometriosis. METHODS All patients had been treated at the Department of Gynecology of the Pedro Ernesto University Hospital, Rio de Janeiro. The study group ...
متن کاملComparison of complete and incomplete excision of deep infiltrating endometriosis.
OBJECTIVE To compare the efficacy and safety of complete and incomplete excision of deep infiltrating endometriosis (DIE). METHODS Ninety-three women who underwent complete excision (n=55) or incomplete surgery of DIE (n=38) between January 2011 and December 2013 were included in this retrospective cohort study. Surgical data, and follow-up information of the patients were analyzed. RESULTS...
متن کاملDeep infiltrating endometriosis of the colon causing cyclic bleeding.
To cite: Ribeiro C, Nogueira F, Guerreiro SC, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2015209464 DESCRIPTION Endometriosis, the presence of functional endometrial tissue outside the uterus, occurs in about 3–10% of women of reproductive age and is a cause of chronic pelvic pain and infertility for some. Bowel involvement may be present in about 5–10...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cells
سال: 2021
ISSN: 2073-4409
DOI: 10.3390/cells10040749